Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331226 | 0.87 | KDM1A (0.47) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL12444183 | 0.85 | KDM1A (0.43) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL2330694 | 0.83 | L3MBTL1 (0.61) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL15097995 | 0.77 | CNR2 (0.42) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL12443332 | 0.74 | CNR2 (0.58) | LMNATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL2330722 | 0.74 | GPR35 (0.50) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL15097977 | 0.73 | CNR2 (0.49) | LMNATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL15097997 | 0.73 | TSHR (0.36) | KDM1ARCOR1L3MBTL1LMNATSHR | |
| SCHEMBL12443718 | 0.72 | CNR2 (0.56) | — | |
| SCHEMBL12443764 | 0.72 | GPR84 (0.46) | LMNASMN1; SMN2MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178453-A1 | Cannabinoid Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178453-A1 | Cannabinoid Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178453-A1 | Cannabinoid Agonists | CNR2, CNR1, GPR18 | KDM1A 2559/4885RCOR1 3023/4885L3MBTL1 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.