Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017646 | 0.80 | ALDH1A1 (0.50) | GRIK1ALDH1A1TDP1SLC7A5 | |
| SCHEMBL18640438 | 0.80 | ALDH1A1 (0.50) | GRIK1ALDH1A1TDP1SLC7A5 | |
| SCHEMBL1017645 | 0.80 | ALDH1A1 (0.50) | GRIK1ALDH1A1TDP1SLC7A5 | |
| SCHEMBL3272877 | 0.78 | TDP1 (0.36) | GRIK1ALDH1A1TDP1 | |
| SCHEMBL27970321 | 0.76 | ALDH1A1 (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL484972 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL11353046 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10691804 | 0.74 | ALDH1A1 (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL2855139 | 0.72 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28281830 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120230937-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | OCCLUGEL (FR) | 2012-09-13 | — | — | US | claimed |
| EP-2475695-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | Occlugel (FR) | 2012-07-18 | — | — | EP | claimed |
| WO-2011029867-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | OCCLUGEL (FR) | 2011-03-17 | — | — | WO | claimed |
| EP-2295480-A1 | Implantable bio-resorbable polymer | Occlugel (FR) | 2011-03-16 | — | — | EP | claimed |
| US-9320804-B2 | Implantable bio-resorbable polymer | OCCLUGEL (FR) | 2016-04-26 | — | — | US | disclosed |
| US-20120230937-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | OCCLUGEL (FR) | 2012-09-13 | — | — | US | disclosed |
| EP-2475695-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | Occlugel (FR) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029867-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | OCCLUGEL (FR) | 2011-03-17 | — | — | WO | disclosed |
| EP-2295480-A1 | Implantable bio-resorbable polymer | Occlugel (FR) | 2011-03-16 | — | — | EP | disclosed |
| EP-0874867-A1 | PARTIALLY CROSS-LINKED MICROSPHERES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997026286-A1 | PARTIALLY CROSS-LINKED MICROSPHERES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120230937-A1 | IMPLANTABLE BIO-RESORBABLE POLYMER | PTH1R, BMP2, BMPR1A | GABRP 303/4885GABRD 981/4885GABRA1 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.