Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969270 | 0.82 | SCN9A (0.32) | CNR2MAPTGAASCN9ACNR1 | |
| SCHEMBL4402626 | 0.81 | ALDH1A1 (0.31) | CYP2C9ALDH1A1MAPTHTT | |
| SCHEMBL7858136 | 0.80 | HTR2C (0.35) | HTR1DHTR1BCYP2C9ALDH1A1MAPT | |
| SCHEMBL12140864 | 0.80 | HTR2C (0.35) | HTR1DHTR1BCYP2C9ALDH1A1MAPT | |
| SCHEMBL15803732 | 0.80 | MCHR1 (0.34) | HTR1DHTR1BCYP2C9ALDH1A1MAPT | |
| SCHEMBL30201447 | 0.80 | HTR2C (0.35) | HTR1DHTR1BCYP2C9ALDH1A1MAPT | |
| SCHEMBL14235296 | 0.79 | SCN9A (0.36) | HTR1DHTR1BCYP2C9CNR2ALDH1A1 | |
| SCHEMBL26209558 | 0.79 | SCN9A (0.36) | HTR1DHTR1BCYP2C9CNR2ALDH1A1 | |
| SCHEMBL4404573 | 0.79 | ALDH1A1 (0.31) | HTR1DHTR1BCYP2C9ALDH1A1MAPT | |
| SCHEMBL9631246 | 0.78 | SCN9A (0.33) | HTR1DHTR1BCYP2C9CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731493-B1 | BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORP (JP) | 2011-03-23 | — | — | EP | disclosed |