Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1405424 | 0.89 | LMNA (0.47) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| SCHEMBL14958465 | 0.89 | LMNA (0.47) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| SCHEMBL17430801 | 0.87 | MAPT (0.37) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| Water SCHEMBL11721226 | 0.87 | LMNA (0.44) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL27898310 | 0.85 | LMNA (0.38) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| SCHEMBL16405718 | 0.82 | MAPT (0.44) | LMNAPSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL3456928 | 0.82 | LMNA (0.40) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL27714839 | 0.81 | PSMD14 (0.47) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| SCHEMBL12931451 | 0.80 | PSMD14 (0.33) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL12192711 | 0.79 | PSMD14 (0.35) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178542-A1 | MONOCATIONIC POLYHYDROXYL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178542-A1 | MONOCATIONIC POLYHYDROXYL COMPOUNDS | CUTA, PAH, PARG | LMNA 1792/4885ALDH1A1 1105/4885PSMD14 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.