Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15105215 | 0.93 | THRA (0.45) | NLRP3MAPK1LMNAPTGS2PKM | |
| SCHEMBL15105025 | 0.92 | THRA (0.50) | NLRP3MAPK1LMNAPTGS2L3MBTL1 | |
| SCHEMBL15105139 | 0.91 | NLRP3 (0.50) | NLRP3MAPK1LMNAPTGS2PKM | |
| SCHEMBL15105458 | 0.91 | THRA (0.52) | NLRP3MAPK1PTGS2L3MBTL1KMT2A | |
| SCHEMBL15105249 | 0.91 | THRA (0.52) | NLRP3MAPK1PTGS2L3MBTL1KMT2A | |
| SCHEMBL15105246 | 0.91 | THRA (0.52) | NLRP3MAPK1PTGS2L3MBTL1KMT2A | |
| SCHEMBL1954918 | 0.89 | NLRP3 (0.52) | NLRP3LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15105456 | 0.84 | KMT2A (0.47) | NLRP3MAPK1LMNAPKMALDH1A1 | |
| SCHEMBL1836314 | 0.83 | THRA (0.43) | L3MBTL1KMT2A | |
| SCHEMBL1955305 | 0.81 | NLRP3 (0.50) | NLRP3MAPK1LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192853-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-12-07 | — | — | US | disclosed |
| EP-2641896-B1 | SEPARATION METHOD | ASAHI CHEMICAL IND (JP) | 2020-10-14 | — | — | EP | disclosed |
| EP-2626345-B1 | SEPARATION METHOD AND METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-9950273-B2 | Method of separation | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-04-19 | — | — | US | disclosed |
| US-9884810-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20140332367-A1 | Method of Separation | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-11-13 | — | — | US | disclosed |
| EP-2641896-A1 | SEPARATION METHOD | Asahi Kasei Chemicals Corporation (JP) | 2013-09-25 | — | — | EP | disclosed |
| EP-2626345-A1 | SEPARATION METHOD AND METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-20130184488-A1 | Separation Method and Method for Producing Isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140332367-A1 | Method of Separation | CCKBR, MAOB, CA9 | NLRP3 4428/4885MAPK1 2939/4885LMNA 1877/4885 |
| US-11192853-B2 | Separation method and method for producing isocyanate | IDH3A, IDH3B, CA9 | NLRP3 3588/4885MAPK1 1889/4885LMNA 1338/4885 |
| US-20130184488-A1 | Separation Method and Method for Producing Isocyanate | IDH3A, IDH3B, CA9 | NLRP3 3588/4885MAPK1 1889/4885LMNA 1338/4885 |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | IDH3A, IDH3B, CA9 | NLRP3 3588/4885MAPK1 1889/4885LMNA 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.