Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221316 | 0.82 | TAAR1 (0.39) | GABRA1GABRB2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31709207 | 0.81 | LMNA (0.39) | ALDH1A1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL2362467 | 0.81 | GABRA1 (0.52) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL170430 | 0.80 | ALDH1A1 (0.50) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL4987129 | 0.80 | ALDH1A1 (0.50) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL5889004 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL6546847 | 0.80 | PDCD1 (0.41) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL15106903 | 0.80 | CYP2A6 (0.50) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL15106837 | 0.80 | MAPK1 (0.50) | GABRA1GABRB2ADRB2ADRB1ALDH1A1 | |
| Bromide SCHEMBL27823869 | 0.79 | GABRA1 (0.49) | GABRA1GABRB2ADRB2ADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309188-B2 | Method for allylating and vinylating aryl, heteroaryl, alkyl, and alkene halogenides using transition metal catalysis | Saitigo GmbH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | SALTIGO GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | VRK2, VRK1, GRK1 | GABRA1 2728/4885GABRB2 3419/4885ADRB2 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.