Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128231 | 0.81 | NFE2L2 (0.43) | PTGER4PTGER3PTGER2NFE2L2TAAR1 | |
| SCHEMBL3128239 | 0.81 | NFE2L2 (0.43) | PTGER4PTGER3PTGER2NFE2L2TAAR1 | |
| SCHEMBL28839595 | 0.80 | NFE2L2 (0.58) | PTGER4PTGER3PTGER2NFE2L2TAAR1 | |
| SCHEMBL8397406 | 0.79 | TAAR1 (0.45) | NFE2L2TAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2033547 | 0.78 | PTGER4 (0.53) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL2033548 | 0.78 | PTGER4 (0.53) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL24075642 | 0.76 | PTGER4 (0.56) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL6546776 | 0.76 | PTGER4 (0.56) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL9035642 | 0.76 | PTGER4 (0.51) | PTGER4PTGER3PTGER2ALDH1A1KDM4E | |
| SCHEMBL1932534 | 0.76 | ALDH1A1 (0.55) | PTGER4PTGER3PTGER2TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309188-B2 | Method for allylating and vinylating aryl, heteroaryl, alkyl, and alkene halogenides using transition metal catalysis | Saitigo GmbH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | SALTIGO GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184485-A1 | Method for Allylating and Vinylating Aryl, Heteroaryl, Alkyl, and Alkene Halogenides Using Transition Metal Catalysis | VRK2, VRK1, GRK1 | PTGER4 3501/4885PTGER3 2375/4885PTGER2 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.