Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310443 | 0.83 | NFE2L2 (0.48) | TAAR1NFE2L2IDO1LMNAKMT2A | |
| SCHEMBL840522 | 0.80 | CHRM5 (0.42) | TAAR1LMNAALDH1A1KMT2AATM | |
| SCHEMBL630637 | 0.80 | NFE2L2 (0.53) | NFE2L2LMNAALDH1A1CYP2A6KMT2A | |
| SCHEMBL15106929 | 0.79 | PTGER4 (0.51) | TAAR1NFE2L2IDO1ALDH1A1KMT2A | |
| SCHEMBL8112257 | 0.78 | NFE2L2 (0.50) | TAAR1NFE2L2IDO1LMNAALDH1A1 | |
| SCHEMBL575057 | 0.75 | TAAR1 (0.50) | TAAR1NFE2L2IDO1LMNAALDH1A1 | |
| SCHEMBL12473708 | 0.75 | TAAR1 (0.50) | TAAR1NFE2L2IDO1LMNAALDH1A1 | |
| SCHEMBL651778 | 0.74 | TAAR1 (0.43) | TAAR1ALDH1A1CYP2A6KMT2ACYP2A13 | |
| SCHEMBL3634562 | 0.73 | TAAR1 (0.48) | TAAR1NFE2L2IDO1LMNAALDH1A1 | |
| SCHEMBL168715 | 0.73 | TAAR1 (0.48) | TAAR1IDO1LMNAALDH1A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |