Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15424627 | 0.80 | POLB (0.59) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11677768 | 0.79 | POLB (0.74) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL21129242 | 0.77 | ALDH1A1 (0.58) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15423533 | 0.77 | PLA2G7 (0.54) | PLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11694927 | 0.75 | POLB (0.68) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2716019 | 0.75 | ALDH1A1 (0.63) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11750487 | 0.75 | ALDH1A1 (0.59) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2135687 | 0.75 | POLB (0.52) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9787811 | 0.74 | POLB (0.65) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13753309 | 0.74 | POLB (0.65) | POLBPLA2G7SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2017-10-12 | — | — | US | disclosed |
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
| US-20160361375-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2016-12-15 | — | — | US | disclosed |
| US-20150175655-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2015-06-25 | — | — | US | disclosed |
| US-20130183262-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183262-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | SLC11A2, ARG1, NGLY1 | POLB 473/4885PLA2G7 2175/4885SMN1; SMN2 2723/4885 |
| US-20150175655-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, SLC10A1, GOT1 | POLB 2009/4885PLA2G7 874/4885SMN1; SMN2 4356/4885 |
| US-20170290827-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, SLC10A1, GOT1 | POLB 2211/4885PLA2G7 797/4885SMN1; SMN2 4128/4885 |
| US-20160361375-A1 | INHIBITORS OF HEPATITIS C VIRUS | HAVCR2, SLC10A1, GOT1 | POLB 2211/4885PLA2G7 797/4885SMN1; SMN2 4128/4885 |
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | SLC11A2, ARG1, NGLY1 | POLB 473/4885PLA2G7 2175/4885SMN1; SMN2 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.