Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15123486 | 0.90 | ABL1 (0.56) | ABL1ALDH1A1HSD17B10CFTRLMNA | |
| SCHEMBL14084581 | 0.88 | ABL1 (0.48) | ABL1ALDH1A1HSD17B10CFTRLMNA | |
| SCHEMBL16756200 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CFTRLMNAPTGDR2 | |
| SCHEMBL15123103 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRLMNAPTGDR2 | |
| SCHEMBL15123457 | 0.81 | PDE7A (0.49) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL5347352 | 0.81 | ABL1 (0.56) | ABL1ALDH1A1HSD17B10CFTRLMNA | |
| SCHEMBL15227031 | 0.79 | PKM (0.46) | ABL1ALDH1A1HSD17B10CFTRLMNA | |
| SCHEMBL15123241 | 0.79 | SLC6A4 (0.49) | ALDH1A1HSD17B10CFTRLMNASLC6A4 | |
| SCHEMBL15143214 | 0.78 | HSD17B10 (0.67) | ALDH1A1HSD17B10CFTRLMNAPTGDR2 | |
| SCHEMBL15123373 | 0.78 | CXCR2 (0.50) | ALDH1A1HSD17B10CFTRLMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200109110-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-04-09 | — | — | US | disclosed |
| US-10287243-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-10287243-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| US-9328067-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-9328067-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-9328067-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20160083342-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. | 2016-03-24 | — | — | US | disclosed |
| US-20160083342-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. | 2016-03-24 | — | — | US | disclosed |
| US-20160083342-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. | 2016-03-24 | — | — | US | disclosed |
| US-8822530-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822530-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822530-B2 | Sulfur derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130252984-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252984-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252984-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130190338-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190338-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190338-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083342-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
| US-20130190338-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
| US-20200109110-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
| US-20130252984-A1 | SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
| US-10287243-B2 | Sulfur derivatives as chemokine receptor modulators | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
| US-11046644-B2 | Sulfur derivatives as chemokine receptor modulators | CX3CR1, CXCR2, CCR2 | ABL1 2744/4885ALDH1A1 2553/4885HSD17B10 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.