SCHEMBL15159293

SCHEMBL15159293

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)Nc1ccc2c(CC(=O)NCNC(=O)CBr)cc(=O)[nH]c2c1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 19/20 0.45
▸ CA2 P00918 19/20 0.45
▸ CA4 P22748 9/20 0.45
▸ CA12 O43570 4/20 0.45
▸ CA9 Q16790 4/20 0.45
▸ TERT O14746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161172 0.87 CA1 (0.48) CA1CA2CA4CA12CA9
SCHEMBL15159292 0.86 CA1 (0.42) CA1CA2CA4CA12CA9
SCHEMBL17365333 0.85 CA1 (0.52) CA1CA2CA4CA12CA9
SCHEMBL14367687 0.80 TERT (0.48) CA1CA2CA4CA12CA9
SCHEMBL12983642 0.77 CA1 (0.42) CA1CA2CA4CA12CA9
SCHEMBL13027061 0.75 CA1 (0.42) CA1CA2CA4CA12CA9
SCHEMBL13273544 0.75 CA1 (0.46) CA1CA2CA4CA12CA9
SCHEMBL17897072 0.74 CA1 (0.36) CA1CA2CA4CA12CA9
SCHEMBL10001927 0.69 TERT (0.40) CA1CA2CA4CA12CA9
SCHEMBL19234764 0.69 TERT (0.43) CA1CA2CA4CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732378-B2 Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-08-15 — — US disclosed
US-20160194690-A1 FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-07-07 — — US disclosed
US-9221759-B2 Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-12-29 — — US disclosed
US-20130202536-A1 FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2013-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202536-A1 FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY CLTA, LARS1, SSB CA1 335/4885CA2 385/4885CA4 139/4885
US-20160194690-A1 FLUOROPHORE CHELATED LANTHANIDE LUMINESCENT PROBES WITH IMPROVED QUANTUM EFFICIENCY CLTA, LARS1, SSB CA1 335/4885CA2 385/4885CA4 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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