Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 14/20 | 0.43 |
| ▸ | CA2 | P00918 | 14/20 | 0.43 |
| ▸ | CA4 | P22748 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161173 | 0.85 | CA1 (0.42) | TERTCA1CA2CA4CA12 | |
| SCHEMBL14367687 | 0.80 | TERT (0.48) | TERTCA1CA2CA4CA12 | |
| SCHEMBL17897072 | 0.80 | CA1 (0.36) | TERTCA1CA2CA4CA12 | |
| SCHEMBL17897073 | 0.76 | KEAP1 (0.35) | TERTCA1CA2CA4CA12 | |
| SCHEMBL23153398 | 0.75 | TERT (0.37) | TERTCA1CA2CA12CA9 | |
| SCHEMBL13273544 | 0.75 | CA1 (0.46) | TERTCA1CA2CA4CA12 | |
| SCHEMBL15161172 | 0.73 | CA1 (0.48) | TERTCA1CA2CA4CA12 | |
| SCHEMBL17365333 | 0.72 | CA1 (0.52) | CA1CA2CA4CA12CA9 | |
| SCHEMBL23130691 | 0.70 | AR (0.53) | — | |
| SCHEMBL15499792 | 0.70 | CA1 (0.75) | CA1CA2CA4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732378-B2 | Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-15 | — | — | US | disclosed |