Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394889 | 0.92 | TSHR (0.84) | TSHRTDP1EPHX1 | |
| SCHEMBL13171313 | 0.90 | TSHR (0.68) | TSHRTDP1ALDH1A1 | |
| SCHEMBL15171908 | 0.89 | TSHR (0.84) | TSHRTDP1 | |
| SCHEMBL10044232 | 0.89 | TSHR (0.84) | TSHRTDP1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL16641682 | 0.88 | TSHR (0.66) | TSHRTDP1EPHX1ALDH1A1 | |
| SCHEMBL92121 | 0.88 | TSHR (0.66) | TSHRTDP1EPHX1ALDH1A1 | |
| SCHEMBL92154 | 0.88 | TSHR (0.64) | TSHRTDP1EPHX1 | |
| SCHEMBL19343438 | 0.86 | TSHR (0.67) | TSHRTDP1 | |
| SCHEMBL10014286 | 0.86 | TSHR (0.64) | TSHRTDP1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL15237110 | 0.85 | TSHR (0.59) | TSHREPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662809-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160236379-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9340001-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9314548-B2 | Nanostructured surfaces for biomedical/biomaterial applications and processes thereof | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150148903-A1 | Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof | LIQUIDIA TECHNOLOGIES, INC. (US) | 2015-05-28 | — | — | US | disclosed |
| US-20150101743-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2015-04-16 | — | — | US | disclosed |
| US-8945441-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140131915-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-20130228950-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-09-05 | — | — | US | disclosed |
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110182805-A1 | Nanoparticle fabrication methods, systems, and materials | NATIONAL SCIENCE FOUNDATION | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182805-A1 | Nanoparticle fabrication methods, systems, and materials | TTN, TAGLN2, TLN1 | TSHR 840/4885TDP1 2295/4885OPRM1 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.