SCHEMBL92121

SCHEMBL92121

CC1(C)CC(NC(=O)OCF)CC(C)(CNC(=O)OCCF)C1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.66
EPHX1 P07099 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16641682 1.00 TSHR (0.66) TSHREPHX1TDP1MAPTMEN1
SCHEMBL13171360 0.91 TSHR (0.64) TSHREPHX1TDP1MAPTMEN1
SCHEMBL18643015 0.91 TSHR (0.64) TSHREPHX1TDP1MAPTMEN1
SCHEMBL13171329 0.91 TSHR (0.80) TSHREPHX1TDP1MAPTMEN1
SCHEMBL47727 0.89 TSHR (0.62) TSHR
SCHEMBL12394889 0.88 TSHR (0.84) TSHREPHX1TDP1
SCHEMBL15171908 0.88 TSHR (0.84) TSHRTDP1
SCHEMBL1753416 0.88 TSHR (0.71) TSHREPHX1TDP1ALDH1A1
SCHEMBL16591356 0.87 TSHR (0.59) TSHREPHX1
SCHEMBL13171313 0.87 TSHR (0.68) TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170259461-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2017-09-14 US disclosed
US-9662809-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2017-05-30 US disclosed
US-20160236379-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2016-08-18 US disclosed
US-9340001-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2016-05-17 US disclosed
US-9314548-B2 Nanostructured surfaces for biomedical/biomaterial applications and processes thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2016-04-19 US disclosed
US-20160038418-A1 NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS NATIONAL SCIENCE FOUNDATION 2016-02-11 US disclosed
US-20150148903-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2015-05-28 US disclosed
US-20150101743-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-04-16 US disclosed
US-8945441-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-02-03 US disclosed
US-20140131915-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-05-15 US disclosed
US-8662878-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-03-04 US disclosed
US-20130202729-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-08-08 US disclosed
US-8444899-B2 Methods and materials for fabricating microfluidic devices THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2013-05-21 US disclosed
US-8439666-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-05-14 US disclosed
US-20120256354-A1 METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-10-11 US disclosed
US-20120189728-A1 METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM LIQUIDIA TECHNOLOGIES, INC. (US) 2012-07-26 US disclosed
US-8128393-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2012-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160038418-A1 NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS TTN, TAGLN2, TLN1 TSHR 840/4885EPHX1 827/4885TDP1 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.