Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 5/20 | 0.39 |
| ▸ | PRKCI | P41743 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398506 | 0.79 | CSNK2A1 (0.44) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL23147918 | 0.79 | AXL (0.37) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL1565481 | 0.79 | CSNK2A1 (0.48) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL9288889 | 0.79 | GPR84 (0.45) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL9887640 | 0.79 | AXL (0.42) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL1474051 | 0.75 | RIPK1 (0.43) | AXLCDK8AHRF7LTA4H | |
| SCHEMBL25613025 | 0.75 | FEN1 (0.37) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL24005526 | 0.75 | CDK8 (0.35) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL29957381 | 0.75 | CYP2A6 (0.41) | AXLPRKCICDK8CSNK2A1PIK3CD | |
| SCHEMBL18984392 | 0.74 | GRIN2D (0.41) | AXLCDK8CSNK2A1RIPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025069270-A1 | AZAINDOLE COMPOUND AND MEDICINE | 日本新薬株式会社 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025070627-A1 | AZAINDOLE COMPOUND AND MEDICAL DRUG | 日本新薬株式会社 | 2025-04-03 | — | — | WO | disclosed |
| CN-103228656-B | 3-substituent-6- (pyridylmethoxy) -pyrrolopyridine compounds | ELI LILLY AND CO. (US) | 2015-09-30 | — | — | CN | disclosed |
| EP-2646437-B1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | LILLY CO ELI (US) | 2014-09-03 | — | — | EP | disclosed |
| EP-2646437-B1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | LILLY CO ELI (US) | 2014-09-03 | — | — | EP | disclosed |
| US-8778946-B2 | 3-substituted-6-(pyridinylmethoxy)-pyrrolopyridine compounds | ELI LILLY AND COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778946-B2 | 3-substituted-6-(pyridinylmethoxy)-pyrrolopyridine compounds | ELI LILLY AND COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778946-B2 | 3-substituted-6-(pyridinylmethoxy)-pyrrolopyridine compounds | ELI LILLY AND COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130225602-A1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225602-A1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225602-A1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225602-A1 | 3-SUBSTITUTED-6-(PYRIDINYLMETHOXY)-PYRROLOPYRIDINE COMPOUNDS | PARK7, SNCA, PINK1 | AXL 4134/4885PRKCI 2794/4885CDK8 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.