Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 3/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862980 | 0.85 | POLB (0.73) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16651881 | 0.79 | EPAS1 (0.49) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26647136 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15434333 | 0.79 | KMT2A (0.57) | SMN1; SMN2TSHRLMNAHTTKMT2A | |
| SCHEMBL19457212 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPK1TSHRPOLBPTGS2 | |
| SCHEMBL17689140 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18074050 | 0.78 | GAA (0.70) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL5715461 | 0.78 | PTGS2 (0.49) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL1489970 | 0.78 | TSHR (0.53) | SMN1; SMN2MAPK1TSHRPOLBLMNA | |
| SCHEMBL21569260 | 0.78 | LMNA (0.62) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245668-B | Process for the preparation of (S) -1- (3-ethoxy-4-methoxyphenyl) -2-methanesulfonylethylamine | 细胞基因公司 | 2017-05-17 | — | — | CN | disclosed |
| EP-2817288-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2817288-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| CN-104245668-A | Process for the preparation of -1- (3-ethoxy-4-methoxyphenyl) -2-methanesulfonylethylamine | CELGENE CORP | 2014-12-24 | — | — | CN | disclosed |
| WO-2013126360-A3 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | CELGENE CORPORATION (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013126360-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013126360-A2 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |