Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211265 | 0.85 | SLC26A4 (0.46) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15211549 | 0.82 | SLC26A4 (0.61) | POLBSLC26A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL15211448 | 0.82 | HDAC8 (0.43) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15212687 | 0.80 | SLC26A4 (0.41) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15211374 | 0.80 | POLB (0.45) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15211565 | 0.78 | HDAC8 (0.46) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15211302 | 0.72 | SLC26A4 (0.44) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL17431465 | 0.72 | HDAC8 (0.44) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15220395 | 0.72 | HDAC8 (0.46) | POLBSLC26A4HDAC8FABP3FABP4 | |
| SCHEMBL15211226 | 0.72 | HDAC8 (0.46) | POLBSLC26A4HDAC8FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |