Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211337 | 0.82 | POLB (0.48) | SLC26A4POLBNR4A2KMT2AKDM4E | |
| SCHEMBL15211487 | 0.81 | KDM4E (0.43) | SLC26A4POLBKMT2AMEN1ACHE | |
| SCHEMBL15211619 | 0.80 | POLB (0.52) | SLC26A4POLBNR4A2KMT2AMEN1 | |
| SCHEMBL15211265 | 0.79 | SLC26A4 (0.46) | SLC26A4POLBNR4A2ALDH1A1GAA | |
| SCHEMBL15211565 | 0.78 | HDAC8 (0.46) | SLC26A4POLBMAOAMAOBKDM4E | |
| SCHEMBL15211374 | 0.78 | POLB (0.45) | SLC26A4POLBNR4A2KMT2ANR4A1 | |
| SCHEMBL24470989 | 0.76 | SLC26A4 (1.00) | SLC26A4POLBNR4A2KMT2AMEN1 | |
| SCHEMBL15212687 | 0.75 | SLC26A4 (0.41) | SLC26A4POLBHPGD | |
| SCHEMBL15211268 | 0.74 | NR4A2 (0.46) | SLC26A4POLBNR4A2KMT2AMEN1 | |
| SCHEMBL15211282 | 0.73 | NR4A2 (0.49) | SLC26A4POLBNR4A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |