Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SLC26A4 | O43511 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211452 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1GAAGLAMAPT | |
| SCHEMBL15211549 | 0.81 | SLC26A4 (0.61) | KDM4EALDH1A1GAAGLAMAPT | |
| SCHEMBL15211654 | 0.75 | PDE5A (0.40) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL15211405 | 0.74 | PPARD (0.40) | ALDH1A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL15211465 | 0.73 | PPARD (0.58) | MAPTTDP1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL437459 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAGLAMAPT | |
| SCHEMBL17444914 | 0.72 | RAB9A (0.49) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL19190806 | 0.71 | PPARD (0.49) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL17431433 | 0.71 | PPARD (0.40) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL20637700 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1GAAGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |