Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211544 | 0.84 | PTPN1 (0.32) | PTPN1ADKKDM4EALDH1A1HPGD | |
| SCHEMBL15211523 | 0.83 | MBOAT4 (0.40) | MBOAT4DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL17444886 | 0.81 | KDM4E (0.37) | MBOAT4POLBKDM4EALDH1A1HPGD | |
| SCHEMBL17431285 | 0.80 | MBOAT4 (0.33) | MBOAT4DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL15211405 | 0.80 | PPARD (0.40) | ALDH1A1HSD17B10ADORA2AMEN1KMT2A | |
| SCHEMBL15211559 | 0.80 | ALDH1A1 (0.45) | DUSP3PTPN5PTPN11CTDSP1POLB | |
| SCHEMBL15211810 | 0.79 | KDM4E (0.38) | DUSP3PTPN5PTPN11CTDSP1POLB | |
| SCHEMBL15211275 | 0.74 | PPARD (0.39) | ADKPOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL15211634 | 0.74 | PPARD (0.36) | ADKKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL15211224 | 0.73 | KDM4E (0.38) | DUSP3PTPN5PTPN11CTDSP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |