Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211522 | 0.84 | MBOAT4 (0.33) | PTPN1ADKGBA1KDM4ENPC1 | |
| SCHEMBL15211371 | 0.82 | PPARD (0.37) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL17431367 | 0.81 | — | — | |
| SCHEMBL15220498 | 0.81 | KDM4E (0.36) | KDM4ENPC1ALDH1A1GLAMAPT | |
| SCHEMBL15211482 | 0.80 | PPARD (0.38) | KDM4ENPC1ALDH1A1GLAMAPT | |
| SCHEMBL15211559 | 0.72 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL15211406 | 0.70 | PIM1 (0.40) | ADKGBA1KDM4EALDH1A1MAPT | |
| SCHEMBL15211705 | 0.69 | MAPT (0.38) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL15211523 | 0.67 | MBOAT4 (0.40) | KDM4EALDH1A1MAPT | |
| SCHEMBL17444886 | 0.65 | KDM4E (0.37) | KDM4ENPC1ALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |