SCHEMBL15211640

SCHEMBL15211640

Nc1ccc(N)c2c1OCCS2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LGMN Q99538 2/20 0.31
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15211772 0.81
SCHEMBL6582231 0.72 MTNR1A (0.43) LMNA
SCHEMBL130553 0.71 MAPT (0.37) LGMNLMNAMAPT
SCHEMBL10335517 0.71
Hydrochloric Acid SCHEMBL9511843 0.69 MAPT (0.37) LGMNLMNAMAPT
SCHEMBL15212201 0.69 LMNA (0.36) LMNAMAPT
SCHEMBL5151322 0.67 LMNA (0.35) LGMNLMNAMAPT
Hydrochloric Acid SCHEMBL9512518 0.66 MAPT (0.34) LGMNLMNAMAPT
SCHEMBL16282448 0.65
SCHEMBL331362 0.64 CTNNB1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9132073-B2 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2015-09-15 US claimed
EP-2816992-A2 NOVEL OXIDATION DYE PRECURSORS Henkel AG & Co. KGaA (DE) 2014-12-31 EP claimed
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-12-11 US claimed
WO-2013124363-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-08-29 WO claimed
US-9132073-B2 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2015-09-15 US disclosed
US-9132073-B2 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2015-09-15 US disclosed
US-9132073-B2 Oxidation dye precursors HENKEL AG & CO. KGAA (DE) 2015-09-15 US disclosed
EP-2816992-A2 NOVEL OXIDATION DYE PRECURSORS Henkel AG & Co. KGaA (DE) 2014-12-31 EP disclosed
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-12-11 US disclosed
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-12-11 US disclosed
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2014-12-11 US disclosed
WO-2013124363-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-08-29 WO disclosed
WO-2013124363-A2 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO. KGAA (DE) 2013-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140359951-A1 NOVEL OXIDATION DYE PRECURSORS KRT18, COXFA4L2, CYB5R3 LGMN 3277/4885LMNA 1657/4885MAPT 1239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.