Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374249 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL8291502 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL29565464 | 0.73 | CTNNB1 (0.41) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL25707671 | 0.73 | MTNR1A (0.43) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL29262317 | 0.73 | CTNNB1 (0.41) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL15211640 | 0.72 | LGMN (0.31) | LMNA | |
| SCHEMBL7526198 | 0.72 | MTNR1A (0.61) | MTNR1AMTNR1BITGB2ICAM1ITGAL | |
| SCHEMBL8481752 | 0.72 | MTNR1A (0.48) | MTNR1AMTNR1BSMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL7524064 | 0.71 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL255962 | 0.69 | ITGB2 (0.52) | MTNR1AITGB2ICAM1ITGALLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |