Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212201 | 0.88 | LMNA (0.36) | LMNAMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL16282420 | 0.79 | CYP3A4 (0.30) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL15212115 | 0.74 | BACE1 (0.32) | MAPTNPC1NPSR1 | |
| SCHEMBL15211828 | 0.73 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL15220647 | 0.73 | NPC1 (0.31) | MAPTNPC1NPSR1 | |
| SCHEMBL15220631 | 0.73 | NPC1 (0.31) | MAPTALDH1A1KDM4ENPC1NPSR1 | |
| SCHEMBL15220637 | 0.73 | HTR1A (0.33) | MAPTALDH1A1NPC1NPSR1TDP1 | |
| SCHEMBL15211938 | 0.72 | NPC1 (0.30) | NPC1 | |
| SCHEMBL15211736 | 0.72 | HTR2A (0.30) | NPC1HTR2AHTR2CHTR2B | |
| SCHEMBL15220640 | 0.70 | NPC1 (0.32) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | claimed |
| EP-2816992-A2 | NOVEL OXIDATION DYE PRECURSORS | Henkel AG & Co. KGaA (DE) | 2014-12-31 | — | — | EP | claimed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | claimed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | claimed |
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | disclosed |
| EP-2816992-A2 | NOVEL OXIDATION DYE PRECURSORS | Henkel AG & Co. KGaA (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | disclosed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | disclosed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | KRT18, COXFA4L2, CYB5R3 | LMNA 1657/4885MAPT 1239/4885ALDH1A1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.