Sugi Predict

Sugi Predict / Compounds / SCHEMBL1521279

SCHEMBL1521279

SCHEMBL1521279

CC(=O)CC(N)(N)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ ALDH1A1 P00352 5/20 0.33
▸ LMNA P02545 2/20 0.33
▸ SLC15A2 Q16348 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ GGT1 P19440 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ HMGCR P04035 1/20 0.32
▸ CHRM1 P11229 1/20 0.32
▸ TBXA2R P21731 1/20 0.32
▸ ADRA1A P35348 1/20 0.32
▸ TRPA1 O75762 1/20 0.32
▸ FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468400 0.77 ALDH1A1 (0.48) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL26747925 0.76 GGT1 (0.46) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL1986433 0.76 GGT1 (0.46) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL681315 0.74 ALDH1A1 (0.33) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL7389222 0.74 TDP1 (0.43) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Hydrochloric Acid SCHEMBL28290715 0.74 GGT1 (0.45) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL7861273 0.74 ALDH1A1 (0.36) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL1332802 0.74 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2TDP1GGT1
Acetic Acid SCHEMBL6374415 0.72 ALDH1A1 (0.43) TSHRCYP2D6CYP2C19HIF1AALDH1A1
Urea SCHEMBL27810939 0.72 ALDH1A1 (0.33) TSHRCYP2D6CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110212890-A1 METASTIN DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-09-01 — — US claimed
EP-2314609-A1 METASTIN DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2011-04-27 — — EP claimed
JP-4653840-B2 — — 2011-03-16 — — JP claimed
US-20110059888-A1 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-03-10 — — US claimed
US-20090298765-A1 Metastin derivatives and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-12-03 — — US claimed
EP-2113513-A2 Metastin derivatives and use thereof Takeda Pharmaceutical Company Limited (JP) 2009-11-04 — — EP claimed
US-20090215700-A1 Metastin derivatives and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-08-27 — — US claimed
EP-2081955-A1 METASTIN DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2009-07-29 — — EP claimed
JP-2009520682-A — — 2009-05-28 — — JP claimed
US-20090105152-A1 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-04-23 — — US claimed
CN-101341168-A Metastin derivatives and use thereof TAKEDA PHARMACEUTICAL (JP) 2009-01-07 — — CN claimed
US-20080312155-A1 Metastin Derivatives and Use Thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-18 — — US claimed
EP-1963362-A1 METASTIN DERIVATIVES AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2008-09-03 — — EP claimed
WO-2008050897-A1 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-05-02 — — WO claimed
WO-2007072997-A1 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-28 — — WO claimed
US-20250099533-A1 ADIPONECTIN PEPTIDOMIMETICS FORMULATIONS ALLYSTA PHARMACEUTICALS INC (US) 2025-03-27 — — US disclosed
US-12201668-B2 Adiponectin peptidomimetics formulations ALLYSTA PHARMACEUTICALS, INC. (US) 2025-01-21 — — US disclosed
WO-2006001499-A2 METASTIN DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-05 — — WO disclosed
US-20040116336-A1 Peptide derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-06-17 — — US disclosed
EP-1270585-A1 PEPTIDE DERIVATIVE Takeda Chemical Industries, Ltd. (JP) 2003-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215700-A1 Metastin derivatives and use thereof SHBG, GNRHR, INHA TSHR 601/4885CYP2D6 3986/4885CYP2C19 3274/4885
US-20080312155-A1 Metastin Derivatives and Use Thereof GNRHR, SHBG, MEN1 TSHR 821/4885CYP2D6 4367/4885CYP2C19 3968/4885
US-20110059888-A1 METASTIN DERIVATIVES AND USE THEREOF SHBG, GNRHR, INHA TSHR 601/4885CYP2D6 3986/4885CYP2C19 3274/4885
US-20090298765-A1 Metastin derivatives and use thereof GNRHR, SHBG, MEN1 TSHR 821/4885CYP2D6 4367/4885CYP2C19 3968/4885
US-20110212890-A1 METASTIN DERIVATIVE AND USE THEREOF GNRHR, SHBG, LHCGR TSHR 1020/4885CYP2D6 4690/4885CYP2C19 3716/4885
US-20090105152-A1 METASTIN DERIVATIVES AND USE THEREOF SHBG, GNRHR, INHA TSHR 758/4885CYP2D6 3470/4885CYP2C19 2703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.