Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763697 | 0.87 | TSHR (0.39) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL5555700 | 0.79 | TSHR (0.33) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL9053522 | 0.77 | ESR1 (0.41) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL16577597 | 0.77 | ESR1 (0.41) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL16577596 | 0.77 | ESR1 (0.41) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL9862892 | 0.75 | TSHR (0.35) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL26667678 | 0.75 | TSHR (0.35) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL9138473 | 0.75 | ESR1 (0.39) | TSHRESR1ESR2MAPTLMNA | |
| SCHEMBL9979264 | 0.73 | TSHR (0.39) | TSHRALDH1A1ESR1ESR2HSD17B10 | |
| SCHEMBL197123 | 0.73 | TSHR (0.39) | TSHRALDH1A1ESR1ESR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013123213-A1 | METHOD OF REDUCING A HALOSILANE COMPOUND IN A MICROREACTOR | DOW CORNING CORPORATION (US) | 2013-08-22 | — | — | WO | disclosed |