SCHEMBL197123

SCHEMBL197123

Cl[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
TDP1 Q9NUW8 5/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
RAB9A P51151 2/20 0.33
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALPG P10696 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28418551 0.97 TSHR (0.37) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL704206 0.97 ESR1 (0.40) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL9586411 0.91 TSHR (0.33) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL9291948 0.84 TSHR (0.33) TSHRTDP1ALDH1A1HSD17B10ESR1
SCHEMBL12816296 0.84 LMNA (0.48) TSHRTDP1ALDH1A1ESR1ESR2
SCHEMBL15410897 0.84 NFE2L2 (0.41) TSHRALDH1A1ESR1ESR2RAB9A
SCHEMBL12817629 0.84 NFE2L2 (0.41) TSHRALDH1A1ESR1ESR2RAB9A
SCHEMBL31454149 0.84 ALDH1A1 (0.48) TDP1ALDH1A1ESR1ESR2RAB9A
SCHEMBL10319120 0.84 ESR1 (0.43) ESR1ESR2MAPTACHE
SCHEMBL3481733 0.84 LMNA (0.48) TSHRTDP1ALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3638 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118306976-B Preparation method of double-layer coated silicon-carbon composite material 晖阳(贵州)新能源材料有限公司 2026-05-12 CN claimed
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
US-12612422-B2 Method for making a siloxane-(meth)acrylate macromonomer DOW SILICONES CORPORATION (US) 2026-04-28 US claimed
US-20250382477-A1 ANTIBACTERIAL THERMOPLASTIC SUBSTRATE GEHR KUNSTSTOFF EXTRUSIONSGESELLSCHAFT MBH (DE) 2025-12-18 US claimed
CN-120157134-A Synthesis of C@SiOx/MoSe based on a SiMo-based metal complex2Method and use of @ OMWCNT material 湖南大学 2025-06-17 CN claimed
WO-2025122450-A1 PHOTOCAGED METAL/METALLOID-ALKOXY AND SILOXANE POLYMER BUILDING BLOCKS AND APPLICATIONS THEREOF BOWLING GREEN STATE UNIVERSITY (US) 2025-06-12 WO claimed
CN-120022404-A Champignon of first fragrant spices of trimethylsilyl modified aerogel load 徐州博康信息化学品有限公司 2025-05-23 CN claimed
CN-120022403-A Aromatherapy taking trimethylsilyl modified aerogel as carrier 徐州博康信息化学品有限公司 2025-05-23 CN claimed
CN-120025537-A Atomic oxygen-resistant polyether-ether-ketone material for aviation, preparation method thereof and composite material 南京工业大学 2025-05-23 CN claimed
EP-4323362-B1 METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES GILEAD SCIENCES INC (US) 2025-05-07 EP claimed
US-4481366-A Process for the preparation of a trifluorovinylsilane, and fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-11-06 US claimed
US-4481279-A Dry-developing resist composition FUJITSU LIMITED (JP) 1984-11-06 US claimed
EP-0119404-A1 Fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-09-26 EP claimed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US claimed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US claimed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US claimed
US-4072710-A FROM SILYL ESTER AND THIONYL CHLORIDE PALOMO COLL A L 1978-02-07 US claimed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US claimed