Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16577597 | 0.83 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL16577596 | 0.83 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL9763697 | 0.82 | TSHR (0.39) | ESR1ESR2MAPTTSHRLMNA | |
| SCHEMBL9138473 | 0.81 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL8939087 | 0.78 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL197544 | 0.77 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL68909 | 0.77 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL15212946 | 0.77 | TSHR (0.35) | ESR1ESR2MAPTTSHRLMNA | |
| SCHEMBL9383203 | 0.77 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL144807 | 0.77 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8277292-A | — | — | None | — | — | JP | disclosed |
| JP-H08277292-A | PRODUCTION OF ORGANIC SILICON COMPOUND | SHIN ETSU CHEM CO LTD | 1996-10-22 | — | — | JP | disclosed |
| US-5389477-A | Containing a metal-free phthalocyanine dye in a resin binder | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |