SCHEMBL5555700

SCHEMBL5555700

Cl[Si](Cl)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763697 0.84 TSHR (0.39) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL15212946 0.79 TSHR (0.35) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL9862892 0.79 TSHR (0.35) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL242095 0.77 ALDH1A1 (0.40) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL9053522 0.74 ESR1 (0.41) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL16577596 0.74 ESR1 (0.41) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL16577597 0.74 ESR1 (0.41) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL9138473 0.72 ESR1 (0.39) TSHRESR1ESR2
SCHEMBL9979264 0.71 TSHR (0.39) TSHRESR1ESR2ALDH1A1HSD17B10
SCHEMBL197123 0.71 TSHR (0.39) TSHRESR1ESR2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2580255-A2 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES The Government of the United States of America as represented by the Secretary of the Navy (US) 2013-04-17 EP disclosed
WO-2011156678-A2 POLYARYLACETYLENES CONTAINING SILOXANE, SILANE, AND CARBORANE MOIETIES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-12-15 WO disclosed
EP-1134224-B1 Cyclosilane compound, and solution composition and process for forming a silicon film JSR CORP (JP) 2007-05-30 EP disclosed
US-6503570-B2 Polysilanes JRS CORPORATION (JP) 2003-01-07 US disclosed
EP-1134224-A2 Cyclosilane compound, and solution composition and process for forming a silicon film JSR Corporation (JP) 2001-09-19 EP disclosed
US-20010021760-A1 Novel cyclosilane compound, and solution composition and process for forming a silicon film JSR CORPORATION (JP) 2001-09-13 US disclosed