Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802771 | 0.86 | MAPT (0.46) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL4776517 | 0.85 | SNCA (0.50) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL29538041 | 0.85 | SNCA (0.50) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL15203579 | 0.84 | DTYMK (0.47) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL11922558 | 0.82 | TDP1 (0.45) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL15797124 | 0.79 | TTR (0.43) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL31439542 | 0.79 | TTR (0.43) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL3958015 | 0.79 | TTR (0.43) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL30957303 | 0.79 | MAPT (0.43) | TTRGPR35MAPTALDH1A1TDP1 | |
| SCHEMBL30076336 | 0.79 | TTR (0.43) | TTRGPR35MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310597-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED P-AMINOPHENOL | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-8519176-B1 | Process for preparation of substituted P-aminophenol | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310597-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED P-AMINOPHENOL | NPEPPS, AASDHPPT, ALPP | TTR 813/4885GPR35 3440/4885MAPT 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.