Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538041 | 1.00 | SNCA (0.50) | SNCAALOX15ALOX12MAPTGPR35 | |
| SCHEMBL15214019 | 0.85 | TTR (0.43) | ALOX15ALOX12MAPTGPR35ALDH1A1 | |
| SCHEMBL14546684 | 0.83 | SNCA (0.46) | SNCAALOX15ALOX12MAPTGPR35 | |
| SCHEMBL9908176 | 0.83 | HTT (0.54) | MAPTCYP3A4KDM4E | |
| SCHEMBL14298925 | 0.82 | DTYMK (0.53) | SNCAALOX15ALOX12MAPTGPR35 | |
| SCHEMBL19373203 | 0.81 | L3MBTL1 (0.39) | MAPTGPR35CYP3A4CA12CA9 | |
| SCHEMBL13483711 | 0.80 | TSHR (0.44) | MAPTGPR35ALDH1A1CYP3A4HPGD | |
| SCHEMBL16808906 | 0.79 | GPR35 (0.49) | SNCAALOX15ALOX12MAPTGPR35 | |
| SCHEMBL16808895 | 0.79 | ALOX15 (0.56) | SNCAALOX15ALOX12GPR35ALDH1A1 | |
| SCHEMBL9744165 | 0.78 | CA12 (0.50) | MAPTGPR35ALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225461-B2 | Compound, substrate for pattern formation, photodegradable coupling agent, pattern formation method, and transistor production method | NIKON CORPORATION (JP) | 2022-01-18 | — | — | US | disclosed |
| US-20190352260-A1 | COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND TRANSISTOR PRODUCTION METHOD | NIKON CORPORATION (JP) | 2019-11-21 | — | — | US | disclosed |
| US-20170285471-A1 | FLUORINE-CONTAINING COMPOSITION, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD AND TRANSISTOR PRODUCTION METHOD | NIKON CORPORATION (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20160152642-A1 | FLOURINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERNING, PHOTODEGRADABLE COUPLING AGENT, PATTERNING METHOD, AND COMPOUND | KANAGAWA UNIVERSITY (JP) | 2016-06-02 | — | — | US | disclosed |
| EP-1991530-A1 | CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | Amgen Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1991540-A1 | CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | Amgen Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-20070265256-A1 | Phosphodiesterase 10 inhibitors | AMGEN INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007098214-A1 | CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007098169-A1 | CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2006028957-A1 | 4-SUBSTITUTED 4, 6-DIALKOXY-CINNOLINE DERIVATIVES AS PHOSPODIESTERASE 10 INHIBITORS FOR THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL SYNDROMS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225461-B2 | Compound, substrate for pattern formation, photodegradable coupling agent, pattern formation method, and transistor production method | CYP3A4, CYP4F11, COASY | SNCA 2423/4885ALOX15 918/4885ALOX12 663/4885 |
| US-20190352260-A1 | COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND TRANSISTOR PRODUCTION METHOD | CYP3A4, CYP4F11, COASY | SNCA 2423/4885ALOX15 918/4885ALOX12 663/4885 |
| US-20070265270-A1 | Cinnoline derivatives as phosphodiesterase 10 inhibitors | PDE7A, PDE10A, PDE7B | SNCA 779/4885ALOX15 2549/4885ALOX12 2962/4885 |
| US-20070265256-A1 | Phosphodiesterase 10 inhibitors | PDE7A, PDE7B, PDE10A | SNCA 794/4885ALOX15 3218/4885ALOX12 3507/4885 |
| US-20160152642-A1 | FLOURINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERNING, PHOTODEGRADABLE COUPLING AGENT, PATTERNING METHOD, AND COMPOUND | AFF1, AFF2, AFF4 | SNCA 3818/4885ALOX15 2363/4885ALOX12 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.