Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302646 | 0.98 | BCL2 (0.56) | BCL2AGXTAOC3FAAHNAAA | |
| SCHEMBL21997278 | 0.94 | GRIA2 (0.50) | BCL2AGXTAOC3FAAHNAAA | |
| SCHEMBL8413101 | 0.87 | MMP3 (0.54) | BCL2SHMT1SHMT2PTGS2GRIA2 | |
| SCHEMBL2305032 | 0.86 | BCL2 (0.59) | BCL2AOC3SHMT1SHMT2PTGS2 | |
| SCHEMBL2304146 | 0.86 | AGXT (0.57) | BCL2AGXTSHMT1SHMT2PTGS2 | |
| SCHEMBL2303566 | 0.86 | BCL2 (0.47) | BCL2AOC3FAAHNAAASHMT1 | |
| SCHEMBL8416493 | 0.86 | BCL2 (0.47) | BCL2AGXTAOC3SHMT1SHMT2 | |
| SCHEMBL2303529 | 0.86 | SHMT1 (0.60) | BCL2AOC3SHMT1SHMT2PTGS2 | |
| SCHEMBL8263689 | 0.85 | CTBP2 (0.49) | BCL2SHMT1SHMT2GRIA2 | |
| SCHEMBL8415008 | 0.85 | GRIA2 (0.58) | BCL2GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103553894-A | Synthetic method of 1, 3-diphenyl-1-acetone | UNIV LIAONING PET CHEM TECH | 2014-02-05 | — | — | CN | claimed |
| CN-108883399-A | Fenfluramine composition and preparation method thereof | 周格尼克斯国际有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-103242372-B | Benzoquinoline triphenylphosphine ring iridium hydrogen adducts and its production and use | LUOYANG NORMAL COLLEGE (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-105439787-A | Method for synthesizing alpha-alkyl ketone | UNIV NANJING SCIENCE & TECH | 2016-03-30 | — | — | CN | disclosed |
| US-9245290-B2 | Caspase inhibitors and uses thereof | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2016-01-26 | — | — | US | disclosed |
| CN-103553894-B | A kind of synthetic method of 1,3-phenylbenzene-1-acetone | LIAOMING PETROCHEMICAL UNIV. (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-103553894-B | A kind of synthetic method of 1,3-phenylbenzene-1-acetone | LIAOMING PETROCHEMICAL UNIV. (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-103553894-B | A kind of synthetic method of 1,3-phenylbenzene-1-acetone | LIAOMING PETROCHEMICAL UNIV. (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-104987284-A | Organic nonlinear optical compound chalcone dibromide synthetic method | TIANCHANG TIANJIA CHEMICAL TECHNOLOGY CO LTD | 2015-10-21 | — | — | CN | disclosed |
| CN-103613487-B | Method for preparing alpha-alkylated ketone by coupling alcohol with alpha-methyl/methylene ketone | UNIV NORTHWEST NORMAL | 2015-06-17 | — | — | CN | disclosed |
| CN-102924201-A | Method for preparing perfluoroalkyl alkyl ketone compound | UNIV DALIAN TECH | 2013-02-13 | — | — | CN | disclosed |
| CN-101273016-B | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV | 2013-01-02 | — | — | CN | disclosed |
| CN-102659539-A | Method for preparing dihydro-chalcones compounds by alpha, beta-unsaturated acyl chloride | UNIV BEIJING CHEMICAL | 2012-09-12 | — | — | CN | disclosed |
| CN-100471832-C | Process to produce a protease inhibitor | PHARMACIA & UPJOHN CO LLC (US) | 2009-03-25 | — | — | CN | disclosed |
| CN-101273016-A | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | CN | disclosed |
| CN-1990452-A | Process to produce a protease inhibitor | UPJOHN CO (US) | 2007-07-04 | — | — | CN | disclosed |
| CN-1298714-C | Novel process for preparing 4-hydroxy-2-oxo-pyran derivatives as protease inhibitors | UPJOHN CO (US) | 2007-02-07 | — | — | CN | disclosed |
| CN-1284763-C | Novel intemediate for preparing 4-hydroxy-2-oxygen-pyran derivatives as protease inhibitor | PHARMACIA & UPJOHN CO LLC (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1511820-A | Novel intemediate for preparing 4-hydroxy-2-oxygen-pyran derivatives as protease inhibitor | �������Ŷ���Լ��������˾ | 2004-07-14 | — | — | CN | disclosed |
| CN-1268947-A | Novel process for preparing 4-hydroxy-2-oxo-pyran derivatives as protease inhibitors | UPJOHN CO (US) | 2000-10-04 | — | — | CN | disclosed |