Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951233 | 0.82 | GAA (0.57) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL6846758 | 0.80 | GAA (0.55) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL1927873 | 0.76 | GAA (0.50) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL827884 | 0.73 | TSHR (0.70) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL29420085 | 0.73 | TSHR (0.70) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL1407867 | 0.73 | GAA (0.47) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL551067 | 0.72 | TSHR (0.61) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL29549724 | 0.72 | TSHR (0.61) | GAATSHRGLAPOLBKIF11 | |
| Hydrochloric Acid SCHEMBL7475459 | 0.72 | GAA (0.46) | GAATSHRGLAPOLBKIF11 | |
| SCHEMBL11927857 | 0.72 | GAA (0.46) | GAATSHRGLAPOLBKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766006-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | NOS2, NOS1, NOS3 | GAA 2283/4885TSHR 1653/4885GLA 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.