Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966171 | 0.82 | TDP1 (0.37) | TDP1 | |
| SCHEMBL4537445 | 0.81 | CPB2 (0.37) | — | |
| SCHEMBL896853 | 0.81 | CPB2 (0.37) | — | |
| SCHEMBL18291030 | 0.81 | GNAI3 (0.37) | MEN1KMT2AGAATDP1PAOX | |
| SCHEMBL15846935 | 0.81 | DPP7 (0.38) | MEN1KMT2AGAATDP1 | |
| SCHEMBL19471168 | 0.80 | MEN1 (0.31) | MEN1KMT2AGAATDP1 | |
| SCHEMBL13799322 | 0.80 | MAPT (0.41) | TDP1FOLH1NPSR1MAPT | |
| SCHEMBL4541834 | 0.79 | MAPT (0.56) | FOLH1MAPT | |
| SCHEMBL22334291 | 0.79 | MEN1 (0.30) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL1882392 | 0.79 | MAPT (0.56) | FOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130224881-A1 | POLYROTAXANES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130224881-A1 | POLYROTAXANES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2013-08-29 | — | — | US | disclosed |