Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1882392 | 0.87 | MAPT (0.56) | MAPTFOLH1 | |
| SCHEMBL4541834 | 0.87 | MAPT (0.56) | MAPTFOLH1 | |
| SCHEMBL15227896 | 0.80 | MAPT (0.50) | MAPTSIRT1FOLH1 | |
| SCHEMBL13812559 | 0.80 | LTA4H (0.46) | MAPTSIRT1KEAP1NFE2L2 | |
| SCHEMBL15215664 | 0.80 | KDM4E (0.39) | MAPTFOLH1NPSR1TDP1 | |
| SCHEMBL7511729 | 0.79 | MAPT (0.53) | MAPTFOLH1 | |
| SCHEMBL26862002 | 0.79 | SIRT1 (0.56) | MAPTSIRT1NPSR1TDP1 | |
| SCHEMBL24945922 | 0.78 | MAPT (0.54) | MAPTFOLH1NPSR1TDP1 | |
| SCHEMBL23278777 | 0.78 | FOLH1 (0.36) | MAPTFOLH1NPSR1TDP1 | |
| SCHEMBL8777364 | 0.78 | FOLH1 (0.50) | MAPTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STUB1, SPR, DBI | MAPT 4339/4885SIRT1 4602/4885KEAP1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.