Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.37 |
| ▸ | EPOR | P19235 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537445 | 1.00 | CPB2 (0.37) | CPB2EPORGSRRNPEPCYP1A2 | |
| SCHEMBL7601678 | 0.90 | CPB2 (0.33) | CPB2EPOR | |
| SCHEMBL5543850 | 0.88 | CPB2 (0.33) | CPB2EPOR | |
| SCHEMBL2567911 | 0.88 | CPB2 (0.33) | CPB2EPOR | |
| SCHEMBL22966171 | 0.87 | TDP1 (0.37) | CTSK | |
| SCHEMBL18291030 | 0.85 | GNAI3 (0.37) | EPOR | |
| SCHEMBL19765214 | 0.83 | EPOR (0.31) | EPOR | |
| SCHEMBL6232124 | 0.82 | EPOR (0.40) | CPB2EPOR | |
| SCHEMBL15215664 | 0.81 | KDM4E (0.39) | — | |
| SCHEMBL6232568 | 0.80 | EPOR (0.40) | CPB2EPORCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346606-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2018-12-06 | — | — | US | disclosed |
| US-10023657-B2 | Reversible protein multimers, methods for their production and use | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2018-07-17 | — | — | US | disclosed |
| US-9606114-B2 | Multivalent chelators containing a scaffold structure for modifying and organizing of target molecules | JOHANN WOLFGANG GOETHE-UNIVERSITAT FRANKFURT AM MAIN (DE) | 2017-03-28 | — | — | US | disclosed |
| US-20130289253-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2013-10-31 | — | — | US | disclosed |
| EP-1778651-B1 | MULTIVALENT CHELATORS FOR MODIFYING AND ORGANIZING OF TARGET MOLECULES | UNIV JW GOETHE FRANKFURT MAIN (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-8198230-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| WO-2012044999-A2 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-04-05 | — | — | WO | disclosed |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2011101445-A1 | HIGH-AFFINITY MULTIVALENT CHELATOR COMPOUNDS (MCHS) AND THEIR USE FOR THE STRUCTURAL AND FUNCTIONAL ANALYSIS OF TARGET MOLECULES | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2011-08-25 | — | — | WO | disclosed |
| US-7956029-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-7514400-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-20080038750-A1 | Multivalent Chelators for Modifying and Organizing of Target Molecules | JOHANN WOLFGANG GOETHE-UNIVERSITAT FRANKFURT AM MAIN (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20060229235-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346606-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | CD4, CD74, CD69 | CPB2 1981/4885EPOR 518/4885GSR 1254/4885 |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | NR1H4, LDLR, NR1H3 | CPB2 1622/4885EPOR 316/4885GSR 3575/4885 |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | CPB2 1105/4885EPOR 155/4885GSR 3341/4885 |
| US-20080038750-A1 | Multivalent Chelators for Modifying and Organizing of Target Molecules | GLMN, SPEN, LGMN | CPB2 2090/4885EPOR 1529/4885GSR 2695/4885 |
| US-20130289253-A1 | REVERSIBLE PROTEIN MULTIMERS, METHODS FOR THEIR PRODUCTION AND USE | CD4, CD74, CD69 | CPB2 1981/4885EPOR 518/4885GSR 1254/4885 |
| US-20060229235-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | CPB2 1105/4885EPOR 155/4885GSR 3341/4885 |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | CPB2 1105/4885EPOR 155/4885GSR 3341/4885 |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | CPB2 1105/4885EPOR 155/4885GSR 3341/4885 |
| US-10023657-B2 | Reversible protein multimers, methods for their production and use | CD4, CD74, CD69 | CPB2 1981/4885EPOR 518/4885GSR 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.