Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135095 | 0.92 | PGR (0.50) | PGRALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL15216064 | 0.82 | ALDH1A1 (0.69) | PGRALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3131662 | 0.82 | MAPT (0.62) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| Hydrochloric Acid SCHEMBL3127773 | 0.81 | MAPT (0.61) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL6686813 | 0.78 | MIF (0.72) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL3127507 | 0.78 | NCOA1 (0.59) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL3131560 | 0.77 | MAPT (0.61) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| Hydrochloric Acid SCHEMBL3134221 | 0.76 | MAPT (0.60) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL3134040 | 0.74 | MAPT (0.64) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL3136890 | 0.74 | XDH (0.56) | ALDH1A1KDM4EHPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021333-B1 | ANTI-PROLIFERATIVE COMPOUNDS DERIVING FROM A 3-ARYL-COUMARINE OR 3-ARYL-QUINOLIN-2-ONE AND USES THEREOF | EOS ETHICAL ONCOLOGY SCIENCE S (IT) | 2010-07-14 | — | — | EP | claimed |