SCHEMBL15216280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21292572	0.79	MAPK1 (0.38)	MAPK1HIF1ASIRT2EPHX2JMJD6
	SCHEMBL7600616	0.78	MAPK1 (0.61)	MAPK1HIF1A
	SCHEMBL12473951	0.77	MAPK1 (0.46)	MAPK1HIF1A
	SCHEMBL18786045	0.77	ADRB2 (0.44)	MAPK1HIF1A
	SCHEMBL18785337	0.77	ESR1 (0.50)	MAPK1HIF1A
	SCHEMBL18785929	0.76	GAA (0.43)	MAPK1HIF1A
	SCHEMBL15216328	0.76	LMNA (0.51)	MAPK1HIF1A
	SCHEMBL18786029	0.76	GAA (0.49)	MAPK1HIF1A
	SCHEMBL18785616	0.76	HPGD (0.45)	MAPK1HIF1A
	SCHEMBL9944399	0.76	L3MBTL1 (0.45)	MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.