Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21107410 | 0.93 | TSHR (0.50) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL10499083 | 0.84 | TSHR (0.65) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL3514269 | 0.84 | TSHR (0.65) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL28060902 | 0.84 | TSHR (0.65) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL10499091 | 0.84 | TSHR (0.65) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL87501 | 0.84 | TSHR (0.77) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL226708 | 0.84 | TSHR (0.77) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL423544 | 0.84 | TSHR (0.77) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| Butane SCHEMBL10783052 | 0.82 | TSHR (0.75) | TSHRTDP1CYP3A4ATMALDH1A1 | |
| SCHEMBL15218683 | 0.81 | CYP3A4 (0.64) | TSHRTDP1CYP3A4ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381140-B2 | Radically polymerisable dental material, cured product and usage | KETTENBACH GMBH & CO. KG (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9381140-B2 | Radically polymerisable dental material, cured product and usage | KETTENBACH GMBH & CO. KG (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9114079-B2 | Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof | KETTENBACH GMBH & CO. KG (DE) | 2015-08-25 | — | — | US | disclosed |
| US-9114079-B2 | Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof | KETTENBACH GMBH & CO. KG (DE) | 2015-08-25 | — | — | US | disclosed |
| US-20150231041-A1 | Radically Polymerisable Dental Material, Cured Product and Usage | KETTENBACH GMBH & CO. KG (DE) | 2015-08-20 | — | — | US | disclosed |
| US-20150231041-A1 | Radically Polymerisable Dental Material, Cured Product and Usage | KETTENBACH GMBH & CO. KG (DE) | 2015-08-20 | — | — | US | disclosed |
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | KETTENBACH GMBH & CO. KG (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | KETTENBACH GMBH & CO. KG (DE) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | ME1, ME2, ME3 | TSHR 4358/4885TDP1 2708/4885CYP3A4 3041/4885 |
| US-20150231041-A1 | Radically Polymerisable Dental Material, Cured Product and Usage | MMAB, MTCL3, TUBB4B | TSHR 2630/4885TDP1 2699/4885CYP3A4 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.