Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508241 | 0.84 | LMNA (0.54) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL29406945 | 0.84 | LMNA (0.54) | CYP3A4TSHRATMTDP1ALDH1A1 | |
| SCHEMBL44320 | 0.84 | CYP3A4 (0.89) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL1833853 | 0.83 | LMNA (0.61) | ALDH1A1LMNAMAPTPRKCAPRKCE | |
| Magnesium SCHEMBL31454400 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL31338802 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL1336595 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL6014128 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL | |
| Ammonia Solution, Strong SCHEMBL16192512 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL | |
| Calcium SCHEMBL31454404 | 0.82 | CYP3A4 (0.86) | CYP3A4TSHRATMTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621455-B1 | POLYMERIZABLE DENTAL MATERIAL COMPRISING A REACTIVE PASTE FORMER, HARDENED DENTAL MATERIAL AND USE THEREOF | KETTENBACH GMBH & CO KG (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-9114079-B2 | Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof | KETTENBACH GMBH & CO. KG (DE) | 2015-08-25 | — | — | US | disclosed |
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | KETTENBACH GMBH & CO. KG (DE) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | ME1, ME2, ME3 | CYP3A4 3041/4885TSHR 4358/4885ATM 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.