Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172662 | 0.81 | LMNA (0.32) | LMNAMAPT | |
| SCHEMBL6893472 | 0.77 | L3MBTL1 (0.39) | MAPT | |
| SCHEMBL6860389 | 0.74 | — | — | |
| SCHEMBL15255816 | 0.73 | — | — | |
| SCHEMBL11346432 | 0.68 | — | — | |
| SCHEMBL6859485 | 0.66 | ELANE (0.42) | MAPT | |
| SCHEMBL15219632 | 0.62 | INMT (0.31) | — | |
| SCHEMBL19283632 | 0.62 | — | — | |
| SCHEMBL6894808 | 0.60 | MEN1 (0.31) | — | |
| SCHEMBL1851994 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513117-B1 | BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-08-28 | — | — | EP | disclosed |