Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19659637 | 0.79 | — | — | |
| SCHEMBL16002318 | 0.78 | INMT (0.35) | INMT | |
| SCHEMBL6894344 | 0.77 | GRM5 (0.33) | — | |
| SCHEMBL2083375 | 0.71 | — | — | |
| SCHEMBL3367604 | 0.68 | ALDH1A1 (0.39) | — | |
| SCHEMBL20347991 | 0.68 | LMNA (0.44) | — | |
| SCHEMBL6893472 | 0.68 | L3MBTL1 (0.39) | — | |
| SCHEMBL11604283 | 0.68 | INMT (0.38) | INMT | |
| SCHEMBL1894549 | 0.66 | — | — | |
| SCHEMBL23747406 | 0.65 | PIK3CD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205633-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | AKARNA THERAPEUTICS, LTD. (GB) | 2017-11-30 | — | — | WO | disclosed |
| EP-2513117-B1 | BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-08-28 | — | — | EP | disclosed |