Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CCKBR | P32239 | 4/20 | 0.58 |
| ▸ | CCKAR | P32238 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.55 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.55 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.55 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251244 | 0.94 | ACE (0.64) | CTSLCTSSCTSKMAPTCCKBR | |
| SCHEMBL8255302 | 0.93 | CCKBR (0.59) | CTSLCTSSCTSKCCKBRCCKAR | |
| SCHEMBL15220151 | 0.92 | CTSL (0.65) | CTSLCTSSCTSKMAPTGAA | |
| SCHEMBL15220104 | 0.92 | CCKBR (0.58) | CTSLCTSSCTSKMAPTCCKBR | |
| SCHEMBL8257569 | 0.91 | PSMB1 (0.66) | CTSLCTSSCTSKMAPTGAA | |
| SCHEMBL8257718 | 0.90 | PSMB1 (0.66) | CTSLCTSSCTSKMAPTGAA | |
| SCHEMBL8255303 | 0.90 | CCKBR (0.56) | CTSLCTSSCTSKMAPTCCKBR | |
| SCHEMBL8256701 | 0.90 | CCKBR (0.70) | CTSLCTSSCTSKMAPTGAA | |
| SCHEMBL8251038 | 0.89 | PSMB1 (0.67) | CTSLCTSSCTSKMAPTGAA | |
| SCHEMBL12706456 | 0.87 | PSMB8 (0.68) | CCKBRCCKARPSMB9PSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865950-B1 | COMPOUNDS USEFUL AS MODULATORS OF THE PROTEASOME ACTIVITY | CENTRE NAT RECH SCIENT (FR) | 2013-08-28 | — | — | EP | disclosed |