Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013357 | 0.93 | KMT2A (0.64) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL4397993 | 0.89 | KMT2A (0.68) | KMT2ALMNAGAARAB9AMAOA | |
| Hydrochloric Acid SCHEMBL322544 | 0.87 | KMT2A (0.66) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL8956279 | 0.85 | KMT2A (0.78) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL4318327 | 0.84 | GAA (0.57) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL4575974 | 0.84 | LMNA (0.87) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL3958934 | 0.82 | KMT2A (0.80) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL17595823 | 0.82 | LMNA (0.79) | KMT2ALMNAGAARAB9AMAOA | |
| SCHEMBL4322690 | 0.82 | KMT2A (0.68) | KMT2ALMNAGAAALDH1A1L3MBTL1 | |
| SCHEMBL27812099 | 0.81 | ALDH1A1 (0.64) | KMT2ALMNAGAARAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |