Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523762 | 0.86 | ERCC5 (0.57) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL3922160 | 0.83 | KMT2A (0.44) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL18341915 | 0.80 | PDE1B (0.57) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL1522863 | 0.78 | FEN1 (0.54) | FEN1ERCC5ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2206340 | 0.76 | ELANE (0.40) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL1716066 | 0.74 | MIF (0.51) | ALDH1A1MIFMEN1KMT2AKDM4E | |
| SCHEMBL2207598 | 0.74 | ELANE (0.38) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL2207892 | 0.72 | HSD17B10 (0.39) | FEN1ERCC5ERCC1ERCC4PDE1B | |
| SCHEMBL1523366 | 0.72 | PTGDR2 (0.51) | ALDH1A1PTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL5613245 | 0.71 | TDP1 (0.41) | FEN1ERCC5ERCC1ERCC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885ERCC1 2041/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885ERCC1 2041/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | FEN1 727/4885ERCC5 3536/4885ERCC1 2534/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | FEN1 1845/4885ERCC5 3596/4885ERCC1 3362/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | FEN1 1213/4885ERCC5 2973/4885ERCC1 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.