Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533268 | 0.83 | LMNA (0.48) | CREBBPBRD4KMT2AMEN1HTT | |
| SCHEMBL2896747 | 0.82 | CREBBP (0.52) | CREBBPBRD4KMT2AMEN1HTT | |
| SCHEMBL2736608 | 0.81 | ALDH1A1 (0.59) | CREBBPBRD4KMT2AMEN1ALDH1A1 | |
| SCHEMBL13702366 | 0.80 | BRD4 (0.54) | CREBBPBRD4KMT2AMEN1HTT | |
| SCHEMBL22479631 | 0.79 | CREBBP (0.52) | CREBBPBRD4KMT2AMEN1HTT | |
| SCHEMBL5909057 | 0.77 | CA12 (0.58) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL13702264 | 0.76 | EPHX2 (0.68) | BRD4KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL13702317 | 0.76 | KCNH2 (0.51) | BRD4KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13702326 | 0.76 | EPHX2 (0.50) | BRD4HTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13701809 | 0.76 | CREBBP (0.50) | CREBBPKMT2AMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524774-B1 | Topical two step polytherapy for treatment of psoriasis and other skin disorders | CYMBIOTICS, INC. (US) | 2013-09-03 | — | — | US | claimed |
| US-8524774-B1 | Topical two step polytherapy for treatment of psoriasis and other skin disorders | CYMBIOTICS, INC. (US) | 2013-09-03 | — | — | US | disclosed |