Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760209 | 0.81 | BRD4 (0.55) | ALDH1A1BRD4HDAC6HDAC2HDAC8 | |
| SCHEMBL15224261 | 0.81 | CREBBP (0.50) | ALDH1A1BRD4LMNARAB9AHPGD | |
| SCHEMBL11900090 | 0.80 | HDAC6 (0.85) | HDAC6HDAC2HDAC8LMNARAB9A | |
| SCHEMBL6533268 | 0.78 | LMNA (0.48) | ALDH1A1BRD4LMNAHPGDPOLB | |
| SCHEMBL2896747 | 0.77 | CREBBP (0.52) | ALDH1A1BRD4LMNARAB9AHPGD | |
| SCHEMBL457082 | 0.76 | HDAC6 (0.79) | ALDH1A1HDAC6HDAC2HDAC8LMNA | |
| SCHEMBL16589429 | 0.76 | HDAC6 (0.72) | ALDH1A1HDAC6HDAC2HDAC8LMNA | |
| SCHEMBL178366 | 0.76 | MAPK14 (0.75) | ALDH1A1HDAC6HDAC2HDAC8LMNA | |
| SCHEMBL29315584 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HDAC6HDAC2HDAC8LMNA | |
| SCHEMBL4747957 | 0.75 | NR1H4 (0.81) | HDAC6HDAC2HDAC8LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | TADA YUKIO | 2010-04-01 | — | — | US | disclosed |
| US-20080312292-A1 | Antipruritics | YASUI KIYOSHI | 2008-12-18 | — | — | US | disclosed |
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | SHIONOGI & CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | CNR2, CNR1, OPRM1 | ALDH1A1 2784/4885BRD4 363/4885HDAC6 2514/4885 |
| US-20100081686-A1 | Pyridone derivatives having a binding activity to the cannabinoid type 2 recepter | CNR2, CNR1, NPY2R | ALDH1A1 3078/4885BRD4 152/4885HDAC6 4752/4885 |
| US-20080312292-A1 | Antipruritics | CNR1, CNR2, OPRL1 | ALDH1A1 3580/4885BRD4 446/4885HDAC6 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.