Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224329 | 1.00 | AKR1B10 (0.42) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224301 | 0.91 | AKR1B10 (0.33) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224319 | 0.91 | AKR1B10 (0.33) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224306 | 0.80 | AKR1B10 (0.44) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15281214 | 0.77 | AKR1B10 (0.34) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224326 | 0.73 | AKR1B10 (0.38) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224343 | 0.73 | AKR1B10 (0.38) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL15224348 | 0.71 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL15224302 | 0.71 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL12846394 | 0.71 | BACE1 (0.48) | PTPN1ALOX5PTGESPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119889726-A | Semen quality prediction method and system based on random forest | 深圳市疾病预防控制中心(深圳市卫生监督局、深圳市卫生检验中心、深圳市预防医学研究所) | 2025-04-25 | — | — | CN | disclosed |
| EP-2633886-B1 | COMPOUNDS AND MIXTURES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-8906958-B2 | Compounds and mixtures for influencing inflammatory states | SYMRISE AG (DE) | 2014-12-09 | — | — | US | disclosed |
| US-8906958-B2 | Compounds and mixtures for influencing inflammatory states | SYMRISE AG (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20130251730-A1 | Compounds and Mixtures Influencing Inflammatory States | SYMRISE AG (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130251730-A1 | Compounds and Mixtures Influencing Inflammatory States | SYMRISE AG (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130236472-A1 | COMPOUNDS AND MIXTURES FOR INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2013-09-12 | — | — | US | disclosed |
| US-20130236472-A1 | COMPOUNDS AND MIXTURES FOR INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2013-09-12 | — | — | US | disclosed |
| EP-2633886-A1 | Compounds and mixtures influencing inflammatory states | Symrise AG (DE) | 2013-09-04 | — | — | EP | disclosed |
| EP-2633885-A1 | Compounds and mixtures for affecting inflammatory conditions | Symrise AG (DE) | 2013-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130251730-A1 | Compounds and Mixtures Influencing Inflammatory States | MSR1, MPO, IL1B | AKR1B10 503/4885AKR1B1 434/4885AKR1C3 196/4885 |
| US-20130236472-A1 | COMPOUNDS AND MIXTURES FOR INFLUENCING INFLAMMATORY STATES | TNF, CXCL8, IL1B | AKR1B10 842/4885AKR1B1 638/4885AKR1C3 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.