Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31717885 | 0.86 | CALM1 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL29207888 | 0.81 | MEN1 (0.71) | PKMALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL29207946 | 0.79 | MEN1 (0.64) | PKMALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2095593 | 0.78 | CA2 (1.00) | CA2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL28091649 | 0.77 | LTA4H (0.55) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL28164756 | 0.74 | CA2 (0.91) | CA2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL29449205 | 0.74 | CA2 (0.91) | CA2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL20871233 | 0.73 | CA2 (0.61) | CA2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL83495 | 0.73 | CA2 (0.80) | CA2ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL21401837 | 0.72 | CHRM2 (0.49) | ALDH1A1LMNATSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266490-B2 | Radioprotector compounds | GEORGETOWN UNIVERSITY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20150044293-A1 | RADIOPROTECTOR COMPOUNDS | GEORGETOWN UNIVERSITY (US) | 2015-02-12 | — | — | US | disclosed |
| US-20150044293-A1 | RADIOPROTECTOR COMPOUNDS | GEORGETOWN UNIVERSITY (US) | 2015-02-12 | — | — | US | disclosed |
| WO-2013138600-A1 | RADIOPROTECTOR COMPOUNDS | ROSEN ELIOT M (US) | 2013-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266490-B2 | Radioprotector compounds | DDB1, CASP3, BAD | CA2 4178/4885PKM 1861/4885ALDH1A1 1017/4885 |
| US-20150044293-A1 | RADIOPROTECTOR COMPOUNDS | DDB1, CASP3, BAD | CA2 4178/4885PKM 1861/4885ALDH1A1 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.