Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310435 | 0.99 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16385957 | 0.89 | RAB9A (0.52) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16385959 | 0.88 | RAB9A (0.51) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12736095 | 0.86 | RAB9A (0.48) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16385954 | 0.86 | RAB9A (0.48) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12736039 | 0.85 | ABL1 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL12736091 | 0.84 | PARP1 (0.48) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15310414 | 0.84 | PARP14 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12736038 | 0.83 | KDM4E (0.52) | L3MBTL3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15310405 | 0.81 | ACHE (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849773-B1 | Piperazine derivatives for the treatment of urinary incontinence and pain | ASTELLAS PHARMA INC (JP) | 2013-10-16 | — | — | EP | claimed |